Alcon Canada

SYSTANE® Extends Tear Film Break-Up Time

SYSTANE® Lubricant Eye Drops demonstrated statistically significant increases in tear film break-up time (TFBUT) through 20 and 30 minutes, respectively.2 SYSTANE® numerically increased TFBUT through 60 minutes.3

There was no statistical difference in the improvement between REFRESH TEARS* and REFRESH ENDURA* at any time point.3

*The tear film break-up time (TFBUT) is the time between a complete blink and the appearance of a dry spot on the surface of the eye. When TFBUT matches or exceeds the time between blinks, the ocular surface is protected.4,5

  1. Christensen MT, Stein JM, Stone RP, Meadows DL. Evaluation of the effect on tear film break-up time extension by artificial tears in dry eye patients. Presented at: 23rd Biennial Cornea Research Conference; October 3-4, 2003; Boston, Mass.
  2. Ousler GW, Emory TB, Welch D, Abelson MB. Factors that influence the inter-blink interval (IBI) as measured by the ocular protection index (OPI). Presented at: The Association of Research in Vision and Ophthalmology (ARVO); 2002.
  3. Nally L, Ousler GW, Abelson MB. Ocular discomfort and tear film break-up time in dry eye patients: a correlation. Invest Ophthalmol Vis Sci. 2000;41(4):1436. ARVO Abstract.
* Trademarks are the properties of their respective owners.

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